Continuous recycling: a mechanism for modulatory signal transduction.
نویسندگان
چکیده
Modulatory signal transduction commonly requires efficient "on demand" assembly of specific multicomponent cellular machines that convert signals to cellular actions. This article suggests that for these signaling machines to detect and respond to fluctuations in signal strength, they must be continuously disassembled in an energy-dependent process that probably involves molecular chaperones.
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ورودعنوان ژورنال:
- Trends in biochemical sciences
دوره 26 5 شماره
صفحات -
تاریخ انتشار 2001