Continuous recycling: a mechanism for modulatory signal transduction.

نویسندگان

  • B C Freeman
  • K R Yamamoto
چکیده

Modulatory signal transduction commonly requires efficient "on demand" assembly of specific multicomponent cellular machines that convert signals to cellular actions. This article suggests that for these signaling machines to detect and respond to fluctuations in signal strength, they must be continuously disassembled in an energy-dependent process that probably involves molecular chaperones.

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عنوان ژورنال:
  • Trends in biochemical sciences

دوره 26 5  شماره 

صفحات  -

تاریخ انتشار 2001